YAN ZHANG,LAN SHEN,SONGFENG LU,KEITH T. DEMAREST,PATRICIA PELTON,GEE-HONG KUO
申请号:
IN4282/KOLNP/2008
公开号:
IN264502B
申请日:
2008.10.22
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
The invention is directed to compounds of Formula (1) useful as PPAR agonists. Pharmaceutical compositions and methods of treating one or more conditions including, but not limited to, diabetes, nephropathy, neuropathy, retinopathy, polycystic ovary syndrome, hypertensions, ischemia, stroke, irritable bowel disorder, inflammation, cataract, cardiovascular diseases, Metabolic X Syndrome, hyper-LDL- cholesterolemia, dyslipidemia (including hypertriglyceridemia, hypercholesterolemia, mixed hyperlipidemia, and hypo-HDL-cholesterolemia), atherosclerosis, obesity, and other disorders related to lipid metabolism and energy homeostasis complications thereof using compounds of the invention and also described.