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ORALLY DISINTEGRATING EXCIPIENT
专利权人:
JRS Pharma
发明人:
David SCHAIBLE,Louis Mejias
申请号:
US15007968
公开号:
US20160136098A1
申请日:
2016.01.27
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention is directed to coprocessed excipient particles comprising a cellulosic material such as microcrystalline cellulose in intimate association with silicon dioxide, a disintegrant and a polyol, sugar or a polyol/sugar blend. The excipient particles display good processing and are useful in prepared compressed solid dosage forms that exhibit rapid disintegration (less than about 60 seconds) when placed on the tongue or when tested according USP disintegration testing, while still providing acceptable mouth feel.
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