HUMAN MATRIX SCIENCES, LLC; LLC;HUMAN MATRIX SCIENCES;THE HOSPITAL FOR SICK CHILDREN
发明人:
JIMENEZ, FELIPE,MITTS, THOMAS F.,HINEK, ALEKSANDER
申请号:
CA2608747
公开号:
CA2608747C
申请日:
2006.05.17
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention describes therapeutic compositions comprisingfibroblasts that have been stimulated to increase expression of extracellularmatrix components or elastin, or to produce enhanced elastogenesis or theappearance thereof at a site of administration. The therapeutic fibroblastformulations can be prepared using a variety of elastogenic agents, includingdigests of mammalian elastin, chemically digested plant extracts comprisingelastin-like peptides, and synthetic elastogenic peptides. The inventionfurther comprises cosmetic and pharmaceutical treatment methods using thetherapeutic fibroblast compositions of the invention.