An ambidextrous locking clamp system (10, 60, 100, 150, 180, 200, 220, 250, 270, 290, 310, 400, 500, 550, 600) for providing a user the ability to use the right or left hand to engage and disengage a ratcheting means on the clamp. The clamp includes hingedly connected first and second elongated members each with a finger engaging member (16, 66, 156, 186, 206, 226, 256, 272, 296, 316, 414, 512, 562, 614), a working head (13, 63, 103, 153, 183, 203, 223, 253, 273, 293, 313, 404, 432, 504, 522, 554, 572, 604, 624, 660, 676), and a latching member (80, 130, 210, 260, 300, 340, 416, 514, 564) featuring ratcheting teeth. The teeth are engaged by moving the finger engaging members (16, 18; 66, 68; 156, 158; 186, 188;, 206, 208; 226, 228; 256, 258; 272, 278;, 296, 298; 316, 318; 414, 440; 512, 528; 562, 578; 614, 632) toward each other in an engaging motion, and are disengaged by sliding them in a disengaging motion perpendicular to the engaging motion with opposing force applied to the finger engaging members (16, 18; 66, 68; 156, 158; 186, 188;, 206, 208; 226, 228; 256, 258; 272, 278;, 296, 298; 316, 318; 414, 440; 512, 528; 562, 578; 614, 632). One of the elongated members includes a planar portion that is rotatably received in a slot (674) defined in a female portion of the other elongated member. The planar portion can include a wedge that contacts a side of the female portion (672) that defines the slot (674) when the clamp is in a closed position.