Mark Shults,James H. Brauker,Victoria Carr-Brendel,Mark Tapsak,Dubravka Markovic
申请号:
US14290842
公开号:
US20140275900A1
申请日:
2014.05.29
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A biointerface membrane for an implantable device including a nonresorbable solid portion with a plurality of interconnected cavities therein adapted to support tissue ingrowth in vivo, and a bioactive agent incorporated into the biointerface membrane and adapted to modify the tissue response is provided. The bioactive agents can be chosen to induce vascularization and/or prevent barrier cell layer formation in vivo, and are advantageous when used with implantable devices wherein solutes are transported across the device-tissue interface.