The invention relates to a device for controlling corporeal structures,especially for introducing puncture needles or operation probes. Said devicecomprises a base plate (1), at least one base holder (2) applied to the baseplate (1), and holding rods (3, 4) that are fixed to the base holder in afixed manner and are used to hold and position a targeting device (10) for amedical instrument (8). The aim of the invention is to create one such devicein such a way that it has a simple structure and can guide medical instrumentsin a variable and precise manner. To this end, the targeting device (10) ismounted on two adjustment arms (7) that can be respectively displaced in the Xand/or Y plane, on the free ends of the holding rods (3, 4), by means of anactuating drive (6).