Compositions and methods of treating carcinoma in an individual afflicted with such a condition, comprising the administration to the individual a therapeutically effective amount of a composition consisting essentially of a nutraceutically acceptable carrier and sodium selenite, with or without menadione. The administration may be sublingual and may be performed in conjunction with injection, into the solid tumor where the carcinoma is a solid tumor, or by intra-arterial catheterization or an organ specific artery where the carcinoma is organ specific, or both.