GERARD, DANIEL EDWARD,SCHOELKOPF, JOACHIM,GANE, PATRICK ARTHUR CHARLES,EBERLE, VERONIKA ANNA,ALLES, RAINER,PUCKHOV, MAXIM,HUWYLER, JÖRG
申请号:
HRP20150558
公开号:
HRP20150558T1
申请日:
2015.05.26
申请国别(地区):
HR
年份:
2015
代理人:
摘要:
An instantly floating gastroretentive drug formulation comprising at least one functionalized natural and/or synthetic calcium carbonate-comprising mineral and at least one pharmaceutically active ingredient and at least one formulating aid wherein said functionalized natural or synthetic calcium carbonate is a reaction product of natural or synthetic calcium carbonate with carbon dioxide and one or more acids, wherein the carbon dioxide is formed in situ by the acid treatment and/or is supplied from an external source.