Tumor therapeutics, the compound indicated by public formula (I) or its pharmaceutically acceptable salt and a kind of combined use of compound for being indicated by public formula (II), the situation being used alone compared to these compounds show excellent antitumaous effect: (wherein ROneC1-6Alkyl or mono- hydrogen atom of C3-8Cycloalkyl, R2Is or mono- hydrogen atom of C1-6Alkoxy, R3Is or a halogen atom.