Novel activator of glucokinase

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专利权人:

リガンド・ファーマシューティカルズ・インコーポレイテッド

发明人:

ティアン・フェン,クン・ダン,ジー・スリダール・プラサド,リ・ウェンユ,ブレット・シー・ブックサー,ニコラス・ブライアン・ラファエル,マーク・ディ・エリオン

申请号：

JP2010521136

公开号：

JP5572549B2

申请日:

2008.08.13

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

The present invention provides for novel compounds of Formulas I and II and pharmaceutically acceptable salts and co-crystals thereof which have glucokinase activator activity. The present invention further provides for pharmaceutical compositions comprising the same as well as methods of treating, preventing, delaying the time to onset or reducing the risk for the development or progression of a disease or condition for which one or more glucokinase activator is indicated, including Type 1 and 2 diabetes, impaired glucose tolerance, insulin resistance and hyperglycemia. The present invention also provides for processes of making the compounds of Formulas I and II, including salts and co-crystals thereof, and pharmaceutical compositions comprising the same.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/