Debra Ondeyka,Xiaoxia Qian,Petr Vachal,Sriram Tyagarajan,Cameron J. Smith,Hong Li,Jianming Bao
申请号:
US14653445
公开号:
US20150342931A1
申请日:
2013.12.17
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Compounds having the structure of Formula (I), including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and may be useful for raising HDL-cholesterol and reducing LDL-cholesterol in human patients and for treating or preventing atherosclerosis. The chemical compounds that are disclosed cholesterol ester transfer protein (CETP) and are expected to have utility in raising HDL-C, lowering LDL-C, and in the treatment and prevention of atherosclerosis.