Fused bicyclic isoxazolines as inhibitors of cholesterol ester transfer protein

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专利权人:

Merck Sharp & Dohme Corp.

发明人:

Pengcheng Patrick Shao,Feng Ye,Petr Vachal

申请号：

US15104351

公开号：

US09663534B2

申请日:

2014.12.12

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, wherein X is (CH2) or O, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis:

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