The Regents of The University of Michigan;University of Newcastle Upon Tyne
发明人:
申请号:
EP14847319.2
公开号:
EP3049073A4
申请日:
2014.09.24
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present disclosure relates to compositions and methods for destabilizing biofilms, altering biofilm 3D structure, and dispersing biofilms, in order to enhance biofilm cell removal and/or sensitivity to other agents (e.g., environmental or co-applied treatments). In particular, the present disclosure relates to the use of L-arginine in the removal and/or sensitization (e.g., to antimicrobials) of microorganisms in medical, industrial, domestic, or environmental applications, as well as treatment of bacterial infections (e.g., in biofilms).