This invention is a new and distinct grapevine variety denominated ‘IFG Twenty-one’. The new grapevine is characterized by producing small naturally seedless red berries having an elliptic shape with a unique combination of muscat and labrusca flavor. The strong fruity flavor is reminiscent of strawberries. Fruits normally ripen very early season about early to mid-July near Delano Calif. Fruits are fairly low in acidity, with medium dense, firm texture. Berries color readily even in hot climatic conditions and produce completely colored bright red berries.