This invention, the phase which is made to contact with the naked nuclear acid where the effective tonnage 1 is isolated at least, includes the said system or the organ which was treated, the manner for transmitting inside the cell of the naked nuclear acid where 1 is isolated at least in, at least phase below, a/said composition vessel or the organ in phase, and the b/phase a which are made to contact at least with the active corticosteroid of 1 of the effective tonnage to biological system or the organ which is isolated, the said phase a/is run, hour period 5 minutes of - 2, regards the above-mentioned manner where phase b/is done at once.< Choice figure >It is not本発明は、単離された生物学的組織又は器官への、少なくとも1の単離された裸の核酸の細胞内伝達のための方法において、少なくとも以下の段階、a/該組成器又は器官を有効量の少なくとも1の活性コルチコステロイドと接触させる段階、及びb/段階aにおいて処理された該組織又は器官を有効量の少なくとも1の単離された裸の核酸と接触させる段階、を含み、該段階a/は5分間~2時間の期間、実行され、直ちに段階b/が行われる上記方法に関する。【選択図】なし
