PAN, TZU MING,潘子明,潘子明,LEE, CHUN LIN,李俊霖,李俊霖,WU, CHENG LUN,吴政伦,吳政倫
申请号:
TW100127357
公开号:
TWI415619B
申请日:
2011.08.02
申请国别(地区):
TW
年份:
2013
代理人:
摘要:
The present invention discloses a composition for lowering blood lipid and elevating high-density lipoprotein and a method for manufacturing the same the composition comprises monascin or ankaflavin, or a combination thereof the manufacturing method comprises the steps of: treating a Monascus fermented product with acetone for three times increasing the concentration of the Monascus fermented product by a process of decompress concentration and extracting the monascin and the ankaflavin from the Monascus fermented product with a silica gel column chromatography, a Sephadex LH-20 column chromatography, the silica gel column chromatography, and a preparative high performance liquid chromatography sequentially.本發明係揭露一種可降血脂且提升高密度脂蛋白膽固醇之組合物及其製造方法,該組合物係包含monascin或是ankaflavin,亦可以同時含有monascin以及ankaflavin;該組合物之製造方法係包含以下步驟:利用丙酮對一紅麴發酵產物反覆進行三次萃取之動作;利用一減壓濃縮之方式提昇其濃度;依序利用一矽膠、一膠濾層析法、一矽膠以及一高效能製備型液相層析法進行分離純化,便可萃取得到monascin以及ankaflavin成分。101~107...本發明第一較佳實施例之製造方法步驟編號