Elena Feinstein,Hagar Kalinski,Huseyin Aygun,Igor Mett,James Mcswiggen,Leonid Beigelman,Rami Skaliter
申请号：
BRPI0817605
公开号：
BRPI0817605A2
申请日:
2008.09.04
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
The invention relates to siRNA compounds possessing novel sequences and structural motifs which down-regulate the expression of specific human genes. The invention also relates to pharmaceutical compositions comprising such compounds and a pharmaceutically acceptable carrier. The present invention also provides a method of treating and/or preventing the incidence or severity of various diseases or conditions associated with the genes and/or symptoms associated with such diseases or conditions comprising administering to a subject in need of treatment for such disease or condition and/or symptom the compound or the pharmaceutical composition in a therapeutically effective dose so as to thereby treat the subject.
