Kalinski, Hagar,Aygun, Huseyin,Skaliter, Rami,Mett, Igor,Beigelman, Leonid,Feinstein, Elena,McSwiggen, James
申请号：
AU2008306455
公开号：
AU2008306455C1
申请日:
2008.09.04
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The invention relates to siRNA compounds possessing novel sequences and structural motifs which down-regulate the expression of specific human genes. The invention also relates to pharmaceutical compositions comprising such compounds and a pharmaceutically acceptable carrier. The present invention also provides a method of treating and/or preventing the incidence or severity of various diseases or conditions associated with the genes and/or symptoms associated with such diseases or conditions comprising administering to a subject in need of treatment for such disease or condition and/or symptom the compound or the pharmaceutical composition in a therapeutically effective dose so as to thereby treat the subject.
