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Pharmaceutical composition comprising rotigotine salts (acid or Na), especially for iontophoresis
专利权人:
UCB PHARMA GMBH
发明人:
BOUWSTRA, J.A.,ACKAERT, O.W.G.M.K.,EIKELENBOOM, J.,WOLFF, HANS-MICHAEL
申请号:
AU2010265087
公开号:
AU2010265087B2
申请日:
2010.06.24
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The present invention relates to new salts of 6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1- ol (rotigotine), their use as a medicament, for example for the treatment of CNS disorders like Parkinson Disease, RLS, fybromyalgia and/or depression, in particular through electromotive administration. The present invention relates to pharmaceutical formulations suitable for iontophoresis that provide enhanced iontophoretic delivery of rotigotine to at least one target tissue. The formulations are further characterized by good to excellent solubility of the salts in aqueous solutions.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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