Johanna Aaltje Bouwstra,Oliver Ackaert,Jacob Eikelenboom,Hans-Michael Wolff
申请号：
US13379333
公开号：
US08754120B2
申请日:
2010.06.24
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to new salts of 6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol (rotigotine), their use as a medicament, for example for the treatment of CNS disorders like Parkinson Disease, RLS, fybromyalgia and/or depression, in particular through electromotive administration. The present invention relates to pharmaceutical formulations suitable for iontophoresis that provide enhanced iontophoretic delivery of rotigotine to at least one target tissue. The formulations are further characterized by good to excellent solubility of the salts in aqueous solutions.
