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Liquid formulations for long-acting erythropoietin conjugate
专利权人:
Min Young Kim;Sung Youb Jung;Dae Seong Im;Chang Ki Lim;Sung Min Bae;Se Chang Kwon
发明人:
Sung Min Bae,Dae Seong Im,Min Young Kim,Chang Ki Lim,Sung Youb Jung,Se Chang Kwon
申请号:
US13574029
公开号:
US08829163B2
申请日:
2011.01.18
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Disclosed is a liquid formulation which allows long-acting EPO conjugates, that have improved in vivo duration and stability, to be stable when stored for a long period of time. It comprises a stabilizer composition characterized by buffer and mannitol. Being free of human serum albumin and other potential factors harmful to the body, the liquid formulation is free of concerns about viral infections and guarantees excellent storage stability to long-acting EPO conjugates.
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