The present Invention is directed to a method for the treatment of Onychomycosis by topical Administration of a composition containing hydroxypropyl quitasano as the only active ingredient and, in particular, by administration of a topical composition for a with Is essentially: hydroxypropyl Chitosan (a) Water, (b), (c) at least a Lower alkanolLa presente invencion esta dirigida a un metodo para el tratamiento de onicomicosis mediante la administracion topica de una composicion que contiene hidroxipropil quitasano como el unico ingrediente activo y, en particular, mediante la administracion de una composicion topica para las unas que consiste esencialmente en: a) hidroxipropil quitosano, b) agua, c) al menos un alcanol inferior