A calcium-based bone cement formula having a powder component and a setting liquid component with a liquid to powder ratio of 0.20 cc/g to 0.50 cc/g is provided, wherein the powder component includes tetracalcium phosphate. The bone cement formula further contains, based on the total weight of the powder component, 0.1-5% of a magnesium setting modifier selected from an oxide, hydroxide, fluoride, chloride, carbonate, phosphate, sulfate and silicate of magnesium.本發明提供了一種具有粉末組分和凝固液體組分的鈣基骨水泥製劑,其中,液體與粉末的比率為0.20 cc/g至0.50 cc/g,所述粉末組分含有磷酸四鈣。該骨水泥製劑進一步含有一用於延長所述骨水泥製劑混合後得到的糊狀物的工作時間和凝固時間的鎂固化調節劑,以所述粉末組分的總重量為基準,所述鎂固化調節劑的含量為0.1-5%,所述鎂固化調節劑為鎂的氧化物,氫氧化物,氟化物,氯化物,碳酸鹽,磷酸鹽,硫酸鹽或矽酸鹽。
