FRANCK LAURENT BREBION,LUKE JONATHAN ALVEY,DAVID AMANTINI,PIERRE MARC MARIE JOSEPH DEPREZ,ROMAIN LUC MARIE GOSMINI,HELÉNE MARIE JARY,CHRISTOPHE PEIXOTO,MARIE LAURENCE CLAIRE VARIN,FRÉDÉRIC ANDRÉ DE CE
申请号：
PT15813831
公开号：
PT3237406T
申请日:
2015.12.18
申请国别(地区):
PT
年份:
2019
代理人:
摘要：
The present invention discloses compounds according to formula I:Wherein R<；sup>；1<；/sup>；, R<；sup>；2<；/sup>；, R<；sup>；3a<；/sup>；, R<；sup>；3b<；/sup>；, and Cy are as defined herein.The present invention relates to compounds inhibiting ADAMTS, methods for their production, pharmaceutical compositions comprising the same, and the compounds of formula I for use in methods of treatment and for use in methods of prophylaxis and/or treatment of inflammatory conditions, and/or diseases involving degradation of cartilage and/or disruption of cartilage homeostasis.
