Spirocyclic morphinans and their use

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专利权人:

パーデュー、ファーマ、リミテッド、パートナーシップ

发明人:

ゴーリング，アール．，リチャード,タフェッセ，レイキア,ヤングマン，マーク，エー．,ゴーリング,アール.,リチャード,タフェッセ,レイキア,ヤングマン,マーク,エー.

申请号：

JP2015547158

公开号：

JP6141444B2

申请日:

2013.12.13

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

The application is directed to compounds of Formula I&prime；-A and especially to compounds of Formula I-A and pharmaceutically acceptable salts and solvates thereof, wherein R1a-R5a, Y, Za are defined as set forth in the specification. The invention is also directed to use of compounds of Formula I&prime；-A, and especially compounds of Formula I-A, to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the present invention are especially useful for treating pain.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/