R. Richard Goehring,Laykea Tafesse,Mark A. Youngman
申请号：
US14105710
公开号：
US08987287B2
申请日:
2013.12.13
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The application is directed to compounds of Formula I′-Aandespecially to compounds of Formula I-Aand pharmaceutically acceptable salts and solvates thereof, wherein R1a-R5a, Y, Za are defined as set forth in the specification. The invention is also directed to use of compounds of Formula I′-A, and especially compounds of Formula I-A, to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the present invention are especially useful for treating pain.
