University of Pittsburgh—Of the Commonwealth System of Higher Education
发明人:
Yuan Chang,Patrick S. Moore
申请号：
US14388418
公开号：
US09662329B2
申请日:
2013.03.26
申请国别(地区):
US
年份:
2017
代理人:
摘要：
A method of treating a polyomavirus (+) cancer in which survivin is upregulated in a patient is provided, comprising administering to the patient a therapeutically effective amount of a composition that downregulates survivin expression or function in cells of the polyomavirus (+) cancer. A method of reducing growth of polyomavirus (+) cancer cells in which survivin is up-regulated is provided, comprising contacting the cells with an amount of a composition that downregulates survivin expression or function effective to reduce growth of the cells. Also provided is sepantronium salt, for use in treating a polyomavirus (+) cancer in which survivin is up-regulated.
