Maria T. Arevalo,Patricia J. Simpson-Haidaris,Xia Jin,Huiyan Chen,Matthew H. Quinn
申请号:
US13701710
公开号:
US20130189275A1
申请日:
2011.06.03
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to a method of interfering with dengue infection comprising interfering with dengue virus binding to a syndecan present on a cell targeted by dengue virus. The present invention further relates to treating a patient for dengue virus infection comprising administering to a patient, either having a dengue infection or a patient exposed to dengue infection, an effective amount of an agent that interferes with dengue virus binding to a syndecan on a surface of a cell targeted by dengue virus. The present invention further relates to a pharmaceutical composition comprising a pharmaceutically acceptable carrier, and an effective amount of an agent that interferes with dengue virus binding to a syndecan on a surface of a cell targeted by dengue virus.