ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA
发明人:
INGENITO, RAFFAELE,JONES, PHILIP,LLAUGER BUFI, LAURA,ONTORIA ONTORIA, JESUS MARIA,SCARPELLI, RITA
申请号：
CA2716918
公开号：
CA2716918C
申请日:
2009.03.13
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention relates to compounds of formula (I) and pharmaceuticallyacceptable salts or tautomersthereof which are inhibitors of poly(ADP-ribose)polymerase (PARP) and thususeful for the treatment of cancer, inflammatorydiseases, reperfusion injuries, ischaemic conditions, stroke, renal failure,cardiovascular diseases, vascular diseases other thancardiovascular diseases, diabetes mellitus, neurodegenerative diseases,retroviral infections, retinal damage, skin senescence andUV-induced skin damage, and as chemo-or radiosensitizers for cancer treatment.
