Ontoria Ontoria, Jesus Maria,Scarpeli, Rita,Schultz-Fademrecht, Carsten,Jones, Philip
申请号:
LT14176452
公开号:
LT2805945T
申请日:
2008.01.08
申请国别(地区):
LT
年份:
2019
代理人:
摘要:
The present invention relates to compounds of formula I: and pharmaceutically acceptable salts, stereoisomers or tautomers thereof which are inhibitors of poly (ADP-ribose) polymerase (PARP) and thus useful for the treatment of cancer, inflammatory diseases, reperfusion injuries, ischemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes, neurodegenerative diseases, retroviral infection, retinal damage or skin senescence and UV-induced skin damage, and as chemo- and/or radiosensitizers for cancer treatment.