The present invention relates to fibrinogen preparations enriched in &alpha；-extended fibrinogen. Compositions comprising such preparations show improved clotting properties compared to preparations based on HMW Fib which typically contain no or only low amounts of &alpha；-extended fibrinogen. In particular, clot formation time and the clot strength of a clot made by &alpha；-extended fibrinogen are improved. In addition, plasmin-mediated degradation of &alpha；-extended fibrinogen is reduced as compared to plasma derived fibrinogen.
