LABORATOIRE FRANÇAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES
发明人:
Céline MONNET
申请号：
US16495427
公开号：
US20200087394A1
申请日:
2018.03.19
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Disclosed is an antibody targeting at least one ligand from an immune checkpoint, having a region Fc that is mutated in relation to that of a parent antibody and has an improved affinity for the receptor FcgRIIIa (CD16a) and/or a higher ADCC activity than the parent antibody.
