Laboratoire Français du Fractionnement et des Biotechnologies;Laboratoire Français du Fractionnement et des Biotechnologies
发明人:
MONNET, Céline
申请号：
EP18711566.2
公开号：
EP3601342A1
申请日:
2018.03.19
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The invention relates to an antibody targeting at least one ligand from an immune checkpoint, having a region Fc that is mutated in relation to that of a parent antibody and has an improved affinity for the receptor FcgRIIIa (CD16a) and/or a higher ADCC activity than the parent antibody.
