Novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative, method of preparing same and pharmaceutical composition for preventing and treating metabolic disease including same as effective ingredient
Yang, Jin,Kim, Jin Woong,Lee, Han Kyu,Kim, Jae Hyun,Son, Chang Mo,Lee, Kyu Hwan,Choi, Hyung-Ho,Kim, Daehoon,Ha, Tae-Young,Rhee, Jaekeol
申请号:
AU2014254555
公开号:
AU2014254555A1
申请日:
2014.04.17
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The present invention relates to a novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative, a method of preparing same and a pharmaceutical composition for preventing and treating metabolic disease including same as an effective ingredient. The novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative, an optical isomer thereof, or a pharmaceutically acceptable salt thereof, according to the present invention, has an excellent effect on activation of GPR40 protein and thus has excellent promoting effect of insulin secretion; is nontoxic when co-administrated with other drugs and is possibly co-administrated with other drugs; and has excellent effective effect of activating GPR40 protein