CATRON, Nathaniel D.,CHEN, Shuang,GONG, Yuchuan,ZHANG, Geoff G.
申请号:
ES11791401
公开号:
ES2644230T3
申请日:
2011.11.21
申请国别(地区):
ES
年份:
2017
代理人:
摘要:
Salts and crystalline forms of 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-({3-nitro-4-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}-sulfonyl)-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide are suitable active pharmaceutical ingredients for pharmaceutical compositions useful in treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.