CATRON, NATHANIEL D.,CHEN, SHUANG,GONG, YUCHUAN,ZHANG, GEOFF G.
申请号:
SG2013039201
公开号:
SG190361A1
申请日:
2011.11.21
申请国别(地区):
SG
年份:
2013
代理人:
摘要:
Salts and crystalline forms of 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-({3-nitro-4-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}- sulfonyl)-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide are suitable active pharmaceutical ingredients for pharmaceutical compositions useful in treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.