BLACKMAN, Davida,PLUM, Stacy,GARZON-RODRIGUEZ, William,YU, Betty,ROBITAILLE, Martin
申请号:
PH12017501118
公开号:
PH12017501118A1
申请日:
2017.06.15
申请国别(地区):
PH
年份:
2017
代理人:
摘要:
Pharmaceutical compositions comprising plasminogen or a biologically active variant thereof are disclosed. In an embodiment, the composition comprises a tonicity modifier, a bulking agent, and a stabilising agent and has a pH of about 3.0 to about 10.0. In another embodiment, the composition contains an amount of particles in suspension equal to or greater than 10 mm which is lower than 6000 particles per 100 ml, and preferably lower than 2000 particles per 100 ml. Uses of these compositions as a medicament is contemplated. Various therapeutic uses of these pharmaceutical compositions is also contemplated.