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COMPOSITION PHARMACEUTIQUE COMPRENANT DU PLASMINOGENE ET SES UTILISATIONS
专利权人:
INC.;PROMETIC BIO THERAPEUTICS
发明人:
ROBITAILLE, MARTIN,BLACKMAN, DAVIDA,PLUM, STACY,GARZON-RODRIGUEZ, WILLIAM,YU, BETTY
申请号:
CA2971359
公开号:
CA2971359A1
申请日:
2015.12.18
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Pharmaceutical compositions comprising plasminogen or a biologically active variant thereof are disclosed. In an embodiment, the composition comprises a tonicity modifier, a bulking agent, and a stabilising agent and has a pH of about 3.0 to about 10Ø In another embodiment, the composition contains an amount of particles in suspension equal to or greater than 10 µm which is lower than 6000 particles per 100 ml, and preferably lower than 2000 particles per 100 ml. Uses of these compositions as a medicament is contemplated. Various therapeutic uses of these pharmaceutical compositions is also contemplated.
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