GAVARIS, PAUL T.,GEDDES, CHRIS D.,GHOVANLOU, ALI H.
申请号：
CA3005050
公开号：
CA3005050A1
申请日:
2016.11.10
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Systems and methods for determining the osmolarity of a sample are provided. Aspects of the subject methods include contacting a sensing surface of a surface plasmon resonance based sensor with a sample, and generating one or more data sets at at least two wavelengths over a time interval, wherein the data sets are used to determine the osmolarity of the sample. The subject methods find use in determining the osmolarity of a sample, such as a biological sample (e.g., a tear fluid), and in the diagnosis and/or monitoring of various diseases and disorders, such as, e.g., dry eye disease.
