Gavaris, Paul T.,Geddes, Chris D.,Ghovanlou, Ali H.
申请号:
AU2016353151
公开号:
AU2016353151A1
申请日:
2016.11.10
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
Systems and methods for determining the osmolarity of a sample are provided. Aspects of the subject methods include contacting a sensing surface of a surface plasmon resonance based sensor with a sample, and generating one or more data sets at at least two wavelengths over a time interval, wherein the data sets are used to determine the osmolarity of the sample. The subject methods find use in determining the osmolarity of a sample, such as a biological sample (e.g., a tear fluid), and in the diagnosis and/or monitoring of various diseases and disorders, such as, e.g., dry eye disease.