NG SARAH MAN YEE,DONOHUE ANDREW CRAIG,TAIT RUSSELL JOHN,BIRKETT STEPHEN LONSDALE,SULISTIO ADRIAN,BLENCOWE ANTON
申请号:
IN3252/KOLNP/2015
公开号:
IN2015KN03252A
申请日:
2015.10.05
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from prostaglandin analogues, β-blockers and mixtures thereof. The present invention also relates to methods for preparing the polymer conjugates using click chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the treatment of glaucoma.