Sarah Man Yee Ng,Andrew Craig Donohue,Russell John Tait,Stephen Lonsdale Birkett,Adrian Sulistio,Anton Blencowe
申请号：
US14772981
公开号：
US09572892B2
申请日:
2014.03.07
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from prostaglandin analogs, β-blockers and mixtures thereof. The present invention also relates to methods for preparing the polymer conjugates using click chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the treatment of glaucoma.
