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COMBINATION OF ADAPALENE AND BENZOYL PEROXIDE FOR THE TREATMENT OF SEVERE ACNE
专利权人:
GALDERMA RESEARCH & DEVELOPMENT
发明人:
Matthew James LEONI,Michael GRAEBER,Vasant MANNA
申请号:
US15383675
公开号:
US20170095434A1
申请日:
2016.12.19
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention concerns a pharmaceutical composition comprising 0.3% by weight of adapalene or a pharmaceutically acceptable salt thereof and 2.5% by weight of benzoyl peroxide, as active ingredients, for its use by topical administration in the treatment of inflammatory acne lesions. The present invention further concerns regimen for the therapeutic treatment of acne lesions in subjects afflicted with severe acne. The regimen includes topically applying to a subject's skin, as active ingredients, 0.3% by weight adapalene and 2.5% by weight benzoyl peroxide, combined in a single formula that delivers the active ingredients together. The single formula can for example be applied once or twice daily for a period of 8 to 12 weeks.
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