LEONI, MATTHEW JAMES,GRAEBER, MICHAEL,MANNA, VASANT
申请号:
SG11201700449R
公开号:
SG11201700449RA
申请日:
2015.07.16
申请国别(地区):
SG
年份:
2017
代理人:
摘要:
The present invention concerns a pharmaceutical composition comprising 0.3% by weight of adapalene or a pharmaceutically acceptable salt thereof and 2.5% by weight of benzoyl peroxide, as active ingredients, for its use by topical administration in the treatment of inflammatory acne lesions. The present invention further concerns regimen for the therapeutic treatment of acne lesions in subjects afflicted with severe acne. The regimen includes topically applying to a subject's skin, as active ingredients, 0.3% by weight adapalene and 2.5% by weight benzoyl peroxide, combined in a single formula that delivers the active ingredients together. The single formula can for example be applied once or twice daily for a period of 8 to 12 weeks.