A refill head for an oral care implement, such as a toothbrush, wherein the refill head utilizes a specially designed structure for coupling the refill head to an oral care implement handle that ensures proper alignment and simplifies the loading and unloading of the refill head to the oral care implement handle. In one embodiment, the refill head comprises a tubular sleeve forming a cavity and first and second upper cam surfaces that form shoulders within the cavity. The first and second upper cam surfaces are separated by first and second axial slots of different configurations that prevent loading of the refill head onto the oral care implement handle in an improper rotational orientation through interaction with first and second bosses on the oral care implement handle.
