COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
发明人:
ADAMS, TIMOTHY,CHIEFARI, JOHN,HAO, XIAOJUAN,HUANG, FEI,MEAGHER, LAURENCE,SCOBLE, JUDITH,WILLIAMS, CHARLOTTE
申请号：
CA3046541
公开号：
CA3046541A1
申请日:
2017.12.22
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention provides a biocompatible and hydrophilic polymer conjugate comprising a linear, aliphatic copolymer backbone to which is conjugated a binding moiety and an agent. The binding moiety is conjugated to an end of the copolymer backbone and facilitates targeted delivery of the agent. Also provided are methods for preparing such polymer conjugates via free radical polymerisation techniques such as reversible addition fragmentation chain transfer (RAFT) polymerisation and uses of such polymer conjugates in diagnosis or therapy.
