Commonwealth Scientific and Industrial Research Organisation
发明人:
Timothy ADAMS,John CHIEFARI,Xiaojuan HAO,Fei HUANG,Laurence MEAGHER,Judith SCOBLE,Charlotte WILLIAMS
申请号：
US16472333
公开号：
US20190358341A1
申请日:
2017.12.22
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention provides a biocompatible and hydrophilic polymer conjugate comprising a linear, aliphatic copolymer backbone to which is conjugated a binding moiety and an agent. The binding moiety is conjugated to an end of the copolymer backbone and facilitates targeted delivery of the agent. Also provided are methods for preparing such polymer conjugates via free radical polymerisation techniques such as reversible addition fragmentation chain transfer (RAFT) polymerisation and uses of such polymer conjugates in diagnosis or therapy.
