The present invention relates to the immortalization B cells of the neutralizing antibody and this antibody of generation that have specificity to human cytomegalovirus and combined with high-affinity. The antibody of invention also has the efficient for neutralizing and infecting. The invention further relates to the antibody in conjunction with epitope purposes in the diagnosing and treating of screening technique and disease of table note of the ancient Chinese and the antibody and the epitope.本發明涉及對人類巨細胞病毒具有特異性並以高親和力結合的中和抗體以及産生這種抗體的無限增殖化B細胞。發明的抗體還具有中和感染的高效力。本發明還涉及所述抗體所結合的表位的表徵以及所述抗體和所述表位在篩選方法以及疾病的診斷和治療中的用途。
