DIELS GASTON STANISLAS MARCELLA,SCHOENTJES BRUNO,VERSELE MATTHIAS LUC AIMÉ,BERTHELOT DIDIER JEAN CLAUDE,WILLEMS MARC,VIELLEVOYE MARCEL,EMBRECHTS WERNER CONSTANT JOHAN,WROBLOWSKI BERTHOLD,MEERPOEL LIEV
申请号：
IN201627037573
公开号：
IN201627037573A
申请日:
2016.11.03
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
The present invention relates to substituted macrocylic pyrimidine derivatives of Formula (I) wherein the variables have the meaning defined in the claims. The compounds according to the present invention have EF2K inhibitory activity and optionally also Vps34 inhibitory activity. The invention further relates to processes for preparing such novel compounds pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
