Thomas M. Rossi;Agis Kydonieus;Charles G. Arnold;Alfred F. Altomari
发明人:
Charles G. Arnold,Agis Kydonieus,Thomas M. Rossi,Alfred F. Altomari
申请号：
US13667632
公开号：
US09364487B2
申请日:
2012.11.02
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A composition for transdermal delivery of a progestin for progestin hormone therapy is disclosed. Also disclosed is a transdermal delivery device comprising the composition. For progestin-only hormone therapy, the composition contains an anti-oxidant and does not contain an estrogen. For therapy involving a progestin and an estrogen, the composition contains the progestin, the estrogen and an additional anti-oxidant. Methods of improving the stability of progestin-containing compositions comprising oxidative agents are also disclosed. The methods comprise including one or more anti-oxidants in the compositions.
